ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE: AVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNF

用途

pTH (13-34) (human) 是一种人甲状旁腺激素(pTH)片段。

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名称

[ 中文名 ]:
ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE: AVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNF

[ 英文名 ]:
pTH (13-34) (human)

[英文别名 ]:

pTH (13-34) (human)

生物活性

[ 描述 ]:

pTH (13-34) (human) 是一种人甲状旁腺激素(pTH)片段。

[ 相关类别 ]:

研究领域 >> 内分泌

信号通路 >> 其他 >> 甲状腺激素受体

物理化学性质

[ 分子式 ]:
C₁₂₅H₁₉₉N₃₉O₃₃S

[ 分子量 ]:
2808.22

[ 精确质量 ]:
2806.48000

[ PSA ]:
1236.13000

[ LogP ]:
6.30010

[ 折射率 ]:
1.66

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Analysis of the requirements for parathyroid hormone action in renal membranes with the use of inhibiting analogues.

J. Biol. Chem. 250 , 3199-3203, (1975)

Two synthetic analogues of bovine parathyroid hormone (PTH) with NH2-terminal modifications, PTH-(3-34) and [desamino-Ala-1]PTH-(1-34), were found to lack agonist activity but to demonstrate antagonis...

Overproduction and secretion of a novel amino-terminal form of parathyroid hormone from a severe type of parathyroid hyperplasia in uremia.

Clin. J. Am. Soc. Nephrol. 1 , 525-531, (2006)

Measurement of bioactive parathyroid hormone (PTH) is essential for optimal management of bone abnormalities in dialysis patients. This can be accomplished by PTH measurements using third-generation P...

Evolution of the parathyroid hormone (PTH) assay--importance of circulating PTH immunoheterogeneity and of its regulation.

Clin. Lab. 51 , 21-29, (2005)

Most of what we know on PTH bioactivity has been associated with the first 34 amino acids of the PTH structure acting on the type I PTH/PTHrP receptor, leaving little place to the carboxyl-terminal st...

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