硬脂酸钠
硬脂酸钠用途
硬脂酸钠名称
[ CAS 号 ]:
822-16-2
[ 中文名 ]:
硬脂酸钠
[ 英文名 ]:
Sodium stearate
[中文别名 ]:
[英文别名 ]:
- sodium,octadecanoate
- Octadecanoic acid, sodium salt (1:1)
- Octadecanoic acid sodium salt
- octadecanoic acid, sodium salt
- Sodium stearate
- SODIUM OCTADECANOATE
- EINECS 212-490-5
- Stearic Acid, Sodium Salt
- stearic acid sodium salt
- MFCD00036404
硬脂酸钠生物活性
硬脂酸钠物理化学性质
[ 密度 ]:
1.103 g/cm3
[ 沸点 ]:
359.4ºC at 760 mmHg
[ 熔点 ]:
245 - 255ºC
[ 分子式 ]:
C18H35NaO2
[ 分子量 ]:
306.459
[ 闪点 ]:
162.4ºC
[ 精确质量 ]:
306.253479
[ PSA ]:
40.13000
[ LogP ]:
4.99780
[ 外观性状 ]:
白色至灰白色粉末或颗粒
[ 储存条件 ]:
2-8°C
[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.
[ 水溶解性 ]:
SOLUBLE IN COLD AND HOT WATER
硬脂酸钠MSDS
硬脂酸钠毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WI4725000
- CHEMICAL NAME :
- Stearic acid, sodium salt
- CAS REGISTRY NUMBER :
- 822-16-2
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C18-H35-O2.Na
- MOLECULAR WEIGHT :
- 306.52
- WISWESSER LINE NOTATION :
- QV17 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATMPA2 Annals of Tropical Medicine and Parasitology. (Grune & Stratton, Inc., POB 6280, Duluth, MN 55806) V.1- 1907- Volume(issue)/page/year: 32,177,1938
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Vascular - thrombosis distant from injection site
- REFERENCE :
- JCINAO Journal of Clinical Investigation. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1924- Volume(issue)/page/year: 42,860,1963 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 10 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 69445 No. of Facilities: 8011 (estimated) No. of Industries: 75 No. of Occupations: 89 No. of Employees: 98215 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 69445 No. of Facilities: 6021 (estimated) No. of Industries: 60 No. of Occupations: 54 No. of Employees: 98046 (estimated) No. of Female Employees: 35115 (estimated)
硬脂酸钠安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危害码 (欧洲) ]:
Xn
[ 安全声明 (欧洲) ]:
S24/25
[ 危险品运输编码 ]:
UN 3077 9/PG 3
[ WGK德国 ]:
1
[ RTECS号 ]:
WI4725000
[ 海关编码 ]:
2915709000
硬脂酸钠合成路线
硬脂酸钠上下游产品
硬脂酸钠上游产品
硬脂酸钠下游产品
硬脂酸钠制备
1.将硬脂酸加入反应釜中,加热至熔融,再在搅拌下加入NaOH水溶液,在65℃加热2h,pH值控制在8.0~8.5。喷雾干燥得产品。
C17H35C OOH+N a OH→C17H3 5C OON a+H2O
2.将10g硬脂酸溶于100mL 95%乙醇中,用0.5mol/L的氢氧化钠乙醇溶液滴定,以酚酞作指示剂,滴定到等当点后,将析出的硬脂酸钠皂抽滤分出。粗产品可用95%乙醇重结晶,得纯品。
硬脂酸钠海关
[ 海关编码 ]: 2915709000
[ 中文概述 ]:
2915709000. 棕榈酸及其盐和酯、硬脂酸盐、酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 硬脂酸和软脂酸的含量
[ Summary ]:
2915709000. palmitic acid and its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
硬脂酸钠文献
J. Pharm. Sci. 103(7) , 2157-65, (2014)
The major obstacle to glioblastoma pharmacological therapy is the overcoming of the blood-brain barrier (BBB). In literature, several strategies have been proposed to overcome the BBB: in this experim...
Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery.Int. J. Pharm. 486 , 232-41, (2015)
Intravenous injections of propofol emulsions are accompanied by pain likely due to the interaction of the dissolved drug with endothelial cells of the vasculature. It is commonly hypothesized that red...
A drug formulation using an alginate hydrogel matrix for efficient oral delivery of the manganese porphyrin-based superoxide dismutase mimic.Biomater. Sci. 3 , 861-9, (2015)
In order for patients to avail of the therapeutic benefits of antioxidant drugs efficiently and conveniently, a robust oral delivery system needs to be developed. However, a common problem in oral dru...
相关化工产品/化学物质:
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联系人:徐经理
产品详情:硬酯酸钠
公司名:南通润丰石油化工有限公司
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价格:
¥需询单/1kg
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¥88.0/500g
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¥205.9/1kg
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联系人:阿拉丁
产品详情:硬脂酸钠
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¥468.0/2500g
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相关化合物
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