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苏丹Ⅳ

苏丹Ⅳ用途

Sudan IV 是一种脂溶性重氮染料、可用于冰冻或石蜡切片上对脂类、甘油三酯和脂蛋白进行染色。

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苏丹Ⅳ名称

[ CAS 号 ]:
85-83-6

[ 中文名 ]:
苏丹Ⅳ

[ 英文名 ]:
Sudan IV

[中文别名 ]:

[英文别名 ]:

o-Tolylazo-o-tolylazo-β-naphthol
Scarlet Red
EINECS 201-635-8
solvent red percent24
fatredb
AKA501
Solvent Red 24
MFCD00003893
c.i.258
oilredf

苏丹Ⅳ生物活性

[ 描述 ]:

Sudan IV 是一种脂溶性重氮染料、可用于冰冻或石蜡切片上对脂类、甘油三酯和脂蛋白进行染色。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Refat NA, et al. The induction of cytochrome P450 1A1 by sudan dyes. J Biochem Mol Toxicol. 2008 Mar-Apr;22(2):77-84.

苏丹Ⅳ物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
618.8±55.0 °C at 760 mmHg

[ 熔点 ]:
199ºC

[ 分子式 ]:
C₂₄H₂₀N₄O

[ 分子量 ]:
380.442

[ 闪点 ]:
424.4±20.8 °C

[ 精确质量 ]:
380.163696

[ PSA ]:
69.67000

[ LogP ]:
6.66

[ 外观性状 ]:
暗红色至棕色晶体或粉末

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.645

[ 储存条件 ]:
库房低温,通风,干燥

[ 水溶解性 ]:
Insoluble in water; soluble in benzene, methanol, acetone, isopropanol; slightly soluble in ethanol

苏丹ⅣMSDS

苏丹Ⅳ毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL5775000

CHEMICAL NAME :: 2-Naphthol, 1-((4-(o-tolylazo)-o-tolyl)azo)-

CAS REGISTRY NUMBER :: 85-83-6

BEILSTEIN REFERENCE NO. :: 0709018

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C24-H20-N4-O

MOLECULAR WEIGHT :: 380.48

WISWESSER LINE NOTATION :: L66J BNUNR B1 DNUNR B1&& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 512 mg/kg/58W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Embryo

DOSE/DURATION :: 100 mg/L

REFERENCE :: AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,241,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1356 No. of Facilities: 212 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 2432 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1356 No. of Facilities: 1210 (estimated) No. of Industries: 15 No. of Occupations: 23 No. of Employees: 20219 (estimated) No. of Female Employees: 10256 (estimated)

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苏丹Ⅳ安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;T: Toxic;

[ 风险声明 (欧洲) ]:
R36/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
QL5775000

[ 海关编码 ]:
2927000090

苏丹Ⅳ合成路线

苏丹Ⅳ上下游产品

苏丹Ⅳ上游产品

苏丹Ⅳ下游产品

苏丹Ⅳ海关

[ 海关编码 ]: 2927000090

[ 中文概述 ]:
2927000090 其他重氮化合物、偶氮化合物等（包括氧化偶氮化合物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

苏丹Ⅳ文献

Determination of banned 10 azo-dyes in hot chili products by gel permeation chromatography-liquid chromatography-electrospray ionization-tandem mass spectrometry.

J. Chromatogr. A. 1164(1-2) , 120-8, (2007)

An accurate method based on the use of gel permeation chromatography (GPC)-liquid chromatography-tandem mass spectrometry interfaced with electrospray ionization (GPC-LC-ESI-MS/MS) was devised for the...

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

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苏丹Ⅳ