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胸腺曲南

胸腺曲南用途

胸腺肽(RGH-0205)是天然产生的胸腺激素胸腺肽和免疫调节肽的生物活性片段。胸腺肽与TP5具有类似的免疫调节活性,并影响体液和细胞反应[1]。

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胸腺曲南名称

[ CAS 号 ]:
85465-82-3

[ 中文名 ]:
胸腺曲南

[ 英文名 ]:
Thymopoietin II: 32-34

[中文别名 ]:

ARG-LYS-ASP-VAL: RKDV

[英文别名 ]:

Rgh 0205
Thymotrinanum [INN-Latin]
Arg-Lys-Asp
Thymotrinanum
N-(N(sup 2)-L-Arginyl-L-lysyl)-L-aspartic acid
Timotrinan
Timotrinan [INN-Spanish]
L-Aspartic acid,N-(N(sup 2)-L-arginyl-L-lysyl)
Thymotrinan
Thymopoietin II: 32-34

胸腺曲南生物活性

[ 描述 ]:

胸腺肽(RGH-0205)是天然产生的胸腺激素胸腺肽和免疫调节肽的生物活性片段。胸腺肽与TP5具有类似的免疫调节活性,并影响体液和细胞反应[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Heizmann J, et al. Enzymatic cleavage of thymopoietin oligopeptides by pancreatic and intestinal brush-border enzymes. Peptides. 1996;17(7):1083-1089.

胸腺曲南物理化学性质

[ 密度 ]:
1.51g/cm3

[ 分子式 ]:
C₁₆H₃₁N₇O₆

[ 分子量 ]:
417.46100

[ 精确质量 ]:
417.23400

[ PSA ]:
246.74000

[ LogP ]:
0.60820

[ 折射率 ]:
1.633

胸腺曲南毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CI9099033

CHEMICAL NAME :: L-Aspartic acid, N-(N(sup 2)-L-arginyl-L-lysyl)-

CAS REGISTRY NUMBER :: 85465-82-3

LAST UPDATED :: 199407

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H31-N7-O6

MOLECULAR WEIGHT :: 417.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986