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醋酸萘法瑞林

醋酸萘法瑞林用途

Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Nafarelin may be used in the treatment of estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat central precocious puberty, and to control ovarian stimulation in IVF. It is normally delivered via a nasal spray. Nafarelin acetate is marketed by Searle (now part of Pfizer) under the brand name Synarel.
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醋酸萘法瑞林名称

[ CAS 号 ]:
86220-42-0

[ 中文名 ]:
醋酸萘法瑞林

[ 英文名 ]:
nafarelin acetate

[英文别名 ]:

醋酸萘法瑞林物理化学性质

[ 沸点 ]:
1840.1ºC at 760 mmHg

[ 分子式 ]:
C68H89N17O16

[ 分子量 ]:
1400.54000

[ 闪点 ]:
1066.6ºC

[ 精确质量 ]:
1399.67000

[ PSA ]:
518.66000

[ LogP ]:
3.89850

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
2-8°C， 密封， 干燥

醋酸萘法瑞林MSDS

详细MSDS(安全技术说明书)

醋酸萘法瑞林安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

醋酸萘法瑞林文献

Spontaneous reports of seizure in association with leuprolide (lupron depot), goserelin (zoladex implant), and naferelin (synarel nasal spray).

Obstet. Gynecol. 121(5) , 1107, (2013)

[Application of Pfizer drugs in the obstetrics and gynecology practice].

Akush. Ginekol. (Sofiia.) 48 Suppl 1 , 41-4, (2009)

[Some possibilities for application of Pfizer medicines--Prostin 15m, Prostin E2, Prepidil gel, Dostinex, Synarel--in the obstetrician practice].

Akush. Ginekol. (Sofiia.) 46 Suppl 2 , 57-60, (2007)

The authors make a clinical and pharmacological overview of the possibilities of application in the obstetrician practice of part of the medicines of the company Pfiser. Some of these medicines have n...


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推荐生产厂家/供应商：

公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：RS-94991-298

公司名：湖北魏氏化学试剂股份有限公司

区域：武汉市洪山区

价格：
￥需询单/5mg ￥需询单/25mg ￥需询单/10g ￥需询单/50g

联系人：张栋

产品详情：醋酸萘法瑞林

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