鸟苷-3',5'-环一硫代磷酸酯,Sp-异构体钠盐
名称
[ CAS 号 ]:
86562-10-9
[ 中文名 ]:
鸟苷-3',5'-环一硫代磷酸酯,Sp-异构体钠盐
[ 英文名 ]:
guanosine-3',5'-cyclic monophosphorothioate, sp-isomer sodium salt
[英文别名 ]:
- SP-CGMPS TRIETHYLAMINE
- SP-CGMPS NA
- sp-cgmps triethylammonium salt
- SP-CGMPS SODIUM SALT
- CGMPS NA SP-ISOMER
- SP-CGMPS,TEA
物理化学性质
[ 分子式 ]:
C16H27N6O6PS
[ 分子量 ]:
462.46100
[ 精确质量 ]:
462.14500
[ PSA ]:
202.88000
[ LogP ]:
1.17220
[ 外观性状 ]:
白色固体
MSDS
安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危险品运输编码 ]:
NONH for all modes of transport
文献
FEBS Lett. 263 , 47-50, (1990)
The activation of the cGMP-dependent protein kinase and cAMP-dependent protein kinase by the diastereomers of guanosine 3',5'-monophosphorothioate, (Sp)-cGMPS and (Rp)-cGMPS, and 8-chloroguanosine 3',...
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.Proc. Natl. Acad. Sci. U. S. A. 91 , 7583-7587, (1994)
Nitric oxide (NO)-induced relaxation is associated with increased levels of cGMP in vascular smooth muscle cells. However, the mechanism by which cGMP causes relaxation is unknown. This study tested t...
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