2-二乙氨基氯乙烷盐酸盐
2-二乙氨基氯乙烷盐酸盐用途
作为有机合成中间体。用于药物胃复康、氯酚胺枸橼酸盐、延通心的合成。
2-二乙氨基氯乙烷盐酸盐名称
[ CAS 号 ]:
869-24-9
[ 中文名 ]:
2-二乙氨基氯乙烷盐酸盐
[ 英文名 ]:
2-Diethylaminoethylchloride Hydrochloride
[中文别名 ]:
[英文别名 ]:
- (β-Chloroethyl)diethylamine hydrochloride
- β-(Diethylamino)ethyl chloride hydrochloride
- Diethyl(β-chloroethyl)amine hydrochloride
- 2-Diethylamino ethylchloride HCL
- 2-Chloro-N,N-diethylethanamine hydrochloride (1:1)
- MFCD00008385
- β-Chloroethyldiethylamine hydrochloride
- 2-Diethylaminoethylchloride hydrochloride
- Diethyl-β-chloroethylamine hydrochloride
- N,N-Diethyl-β-chloroethylamine hydrochloride
2-二乙氨基氯乙烷盐酸盐物理化学性质
[ 沸点 ]:
255 °C(lit.)
[ 熔点 ]:
50-53 °C(lit.)
[ 分子式 ]:
C6H15Cl2N
[ 分子量 ]:
172.096
[ 闪点 ]:
186 °F
[ 精确质量 ]:
171.058151
[ PSA ]:
3.24000
[ LogP ]:
2.36900
[ 外观性状 ]:
透明至米色晶体
[ 储存条件 ]:
Poison room
[ 水溶解性 ]:
2000 g/L (20 ºC)
2-二乙氨基氯乙烷盐酸盐MSDS
2-二乙氨基氯乙烷盐酸盐毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YE1050000
- CHEMICAL NAME :
- Triethylamine, 2-chloro-, hydrochloride
- CAS REGISTRY NUMBER :
- 869-24-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 21
- MOLECULAR FORMULA :
- C6-H14-Cl-N.Cl-H
- MOLECULAR WEIGHT :
- 172.12
- WISWESSER LINE NOTATION :
- G2N2&2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 103 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 71 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 42 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 22 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,33,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7462 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4354 (estimated) No. of Female Employees: 729 (estimated)
2-二乙氨基氯乙烷盐酸盐安全信息
[ 符号 ]:
GHS05, GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H300 + H310 + H330-H315-H318-H335
[ 警示性声明 ]:
Missing Phrase - N15.00950417-P280-P302 + P352 + P310-P304 + P340 + P310-P305 + P351 + P338 + P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
Xn, T, Xi, T+
[ 风险声明 (欧洲) ]:
R24/25;R26;R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36-S45-S36/37/39-S28A
[ 危险品运输编码 ]:
UN 2811 6.1/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
DC2810000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1
[ 海关编码 ]:
29211980
2-二乙氨基氯乙烷盐酸盐合成路线
2-二乙氨基氯乙烷盐酸盐上下游产品
2-二乙氨基氯乙烷盐酸盐上游产品
2-二乙氨基氯乙烷盐酸盐下游产品
2-二乙氨基氯乙烷盐酸盐制备
由N,N’-二乙氨基乙醇与氯化亚砜反应而得。
2-二乙氨基氯乙烷盐酸盐海关
[ 海关编码 ]: 29211980
2-二乙氨基氯乙烷盐酸盐文献
Gig. Tr. Prof. Zabol. (2) , 54-6, (1985)
Allergic and irritant contact dermatitis from diethyl-beta-chloroethylamine.
Contact Dermatitis 18(2) , 103-5, (1988)
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：[Perfemiker]2-二乙氨基氯乙烷盐酸盐,99%
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥278.0/500g
￥88.0/100g
联系人：刘佳
产品详情：2-二乙氨基氯乙烷盐酸盐
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