水杨醛
水杨醛用途
主要用途:用作分析试剂、香料、汽油添加剂及用于有机合成
【用途二】
有机合成原料，用于制造香豆素和配制紫罗兰等香精，也用作杀虫剂
【用途三】
用作分析试剂，也用于有机合成
【用途四】
GB 2760--1996规定为允许使用的食用香料。主要用以配制肉桂和坚果类香精。
【用途五】
该品为香料和其他有机合成的中间体。我国GB 2760-86规定为允许使用的食用香料，主要用以配制肉桂和坚果香精。
【用途六】
肼的检定。钪的光度测定。镍与钴的萃取分离。检验镍、铜、及杂醇与酮类的恶臭、有机合成。香料。
水杨醛名称
[ CAS 号 ]:
90-02-8
[ 中文名 ]:
2-羟基苯甲醛
[ 英文名 ]:
Salicylaldehyde
[中文别名 ]:
[英文别名 ]:
- salicyaldehyde
- FEMA 3004
- 2-hydroxylphenylaldehyde
- 2-hydroxyl-1-benzaldehyde
- MFCD00003317
- Salicylaldehyde
- 2-FORMYLPHENOL
- salicyladehyde
- Salicylal
- o-Formylphenol
水杨醛物理化学性质
[ 密度 ]:
1.146 g/mL at 25 °C(lit.)
[ 沸点 ]:
197 °C(lit.)
[ 熔点 ]:
1-2 °C(lit.)
[ 分子式 ]:
C7H6O2
[ 分子量 ]:
122.12100
[ 闪点 ]:
170 °F
[ 精确质量 ]:
122.03700
[ PSA ]:
37.30000
[ LogP ]:
1.20470
[ 外观性状 ]:
透明油性液体
[ 蒸汽密度 ]:
4.2 (vs air)
[ 蒸汽压 ]:
1 mm Hg ( 33 °C)
[ 折射率 ]:
n20/D 1.573(lit.)
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放
[ 稳定性 ]:
Stable. Combustible. Incompatible with strong bases, strong reducing agents, strong acids, strong oxidizing agents.
[ 水溶解性 ]:
slightly soluble
水杨醛MSDS
水杨醛毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VN5250000
- CHEMICAL NAME :
- Salicylaldehyde
- CAS REGISTRY NUMBER :
- 90-02-8
- BEILSTEIN REFERENCE NO. :
- 0471388
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C7-H6-O2
- MOLECULAR WEIGHT :
- 122.13
- WISWESSER LINE NOTATION :
- VHR BQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,903,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 520 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,903,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,903,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,903,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 504 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533438
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 231 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 16,371,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,903,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533438 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 38,209,1982
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 38,209,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80207 No. of Facilities: 49 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 418 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80207 No. of Facilities: 723 (estimated) No. of Industries: 9 No. of Occupations: 6 No. of Employees: 4597 (estimated) No. of Female Employees: 234 (estimated)
水杨醛安全信息
[ 符号 ]:
GHS07, GHS09
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H411
[ 警示性声明 ]:
P273-P301 + P312 + P330-P391-P501
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful
[ 风险声明 (欧洲) ]:
R21/22;R36/38
[ 安全声明 (欧洲) ]:
S26-S36/37-S36/37/39
[ 危险品运输编码 ]:
3082
[ WGK德国 ]:
2
[ RTECS号 ]:
VN5250000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1(b)
水杨醛合成路线
水杨醛上下游产品
水杨醛上游产品
水杨醛下游产品
水杨醛制备
1.将苯酚和过量的氢氧化钠混合,配成酚钠溶液，加热至60～65℃，缓缓加入氯仿，反应最初为紫色，渐渐转为橙红色，反应完毕后，将过剩的氯仿用水蒸气蒸出，生成的水杨醛钠盐经酸中和后，再通水蒸气蒸出水杨醛即可。
2.将邻甲苯酚与三氯氧磷混合后，在一定温度下反应，生成磷酸三邻甲苯酚酯。然后通入氯气至生成α- α -二氯衍生物为止，最后，经水解蒸馏得高收率，高含量的水杨醛产品。主要反应如下：
3. 水杨苷法，即水杨苷 （ 或水杨醇）在铂或钯催化剂的存在下，空气氧化制得。也可由苯酚作起始原料制备。反应式如下：
水杨醛文献
Bioorg. Med. Chem. 15 , 2006-15, (2007)
Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-q...
Highly selective silver nanoparticles based label free colorimetric sensor for nitrite anions.Anal. Chim. Acta 842 , 57-62, (2014)
Highly selective label free colorimetric sensor based on AgNPs stabilized by phenolic chelating ligand, N,N'-bis(2-hydroxybenzyl)-1,2-diaminobenzene (1), for NO(2-) anions has been developed. Addition...
Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation.Cancer Res. 75 , 2211-21, (2015)
Iron homeostasis is disrupted in multiple myeloma, a difficult-to-cure plasma cell malignancy with lytic bone lesions. Here, we systematically analyzed iron gene expression signature and demonstrated ...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥118.0/500ml
联系人：刘佳
产品详情：水杨醛
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：水杨醛
公司名：西安康诺化工有限公司
区域：西安市雁塔区
价格：
￥需询单/1kg
联系人：高经理
产品详情：水杨醛
查看所有供应商请点击：
相关化合物
【水杨醛】化源网提供水杨醛CAS号90-02-8，水杨醛MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询水杨醛上化源网，专业又轻松。>>电脑版：水杨醛
标题：水杨醛_MSDS_用途_密度_水杨醛CAS号【90-02-8】_化源网 地址：https://m.chemsrc.com/mip/cas/90-02-8_441458.html