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醛缩酶

醛缩酶用途

1.用于生化研究，临床上用于诊断心肌梗死。用于1,6-二磷酸-D-果糖的测定。

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醛缩酶名称

[ CAS 号 ]:
9024-52-6

[ 中文名 ]:
醛缩酶

[ 英文名 ]:
aldolase

[中文别名 ]:

[英文别名 ]:

iub: 4.1.2.13
fructose-diphosphate aldolase
aldolase ammonium sulfate
aldolase
aldolase rabbit muscle
MFCD00130453
ec 4.1.2.13

醛缩酶生物活性

[ 描述 ]:

醛缩酶是一种糖酵解酶,也是VATPase复合物的组成部分。醛缩酶使1,6-二磷酸果糖分解为二羟基丙酮和3-磷酸甘油醛[1]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Li M, et al. Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1. Cell Res. 2021 Apr;31(4):478-481.

醛缩酶物理化学性质

[ 分子式 ]:
n_.a_.

[ 外观性状 ]:
powder | white

[ 储存条件 ]:
2-8°C

醛缩酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36-24/25-22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

醛缩酶制备

以兔肌为原料，绞碎匀浆后提取，取上清液用硫酸铵分级沉淀得粗品，再经离心、重结晶后得纯品。

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醛缩酶文献

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

Sci. Signal. 2 , ra46, (2009)

Protein phosphorylation events during T cell receptor (TCR) signaling control the formation of complexes among proteins proximal to the TCR, the activation of kinase cascades, and the activation of tr...

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

The first identification of lysine malonylation substrates and its regulatory enzyme.

Mol. Cell. Proteomics 10(12) , M111.012658, (2011)

Protein post-translational modifications (PTMs) at the lysine residue, such as lysine methylation, acetylation, and ubiquitination, are diverse, abundant, and dynamic. They play a key role in the regu...

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醛缩酶