肌酐酶

肌酐酶用途

肌酸激酶(Creatinine amidohydrase；CAH),即来自假单胞菌putida的肌酸酐酰胺水解酶,是一种常用于生化研究的同六聚体酶。肌酸酶作用于肽键以外的碳氮键,可以催化肌酐水解为肌酸,然后肌酸酶可以代谢为尿素和肌氨酸[1]。

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肌酐酶名称

[ CAS 号 ]:
9025-13-2

[ 中文名 ]:
肌酐酶

[ 英文名 ]:
Native Pseudomonas sp. Creatinine amidohydrolase

[英文别名 ]:

Creatinine amidohydrolase
Ethanone, 2,2,2-trifluoro-1-(4-methylphenyl)-
2,2,2-Trifluoro-1-p-tolyl-ethanone
2,2,2-Trifluoro-1-(4-methylphenyl)ethanone
Creatinine amide hydrolase
Native Pseudomonas sp. Creatinine amidohydrolase

肌酐酶生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Barbara Beuth, et al. Crystal structure of creatininase from Pseudomonas putida: a novel fold and a case of convergent evolution. J Mol Biol. 2003 Sep 5;332(1):287-301.

肌酐酶物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
194.5±35.0 °C at 760 mmHg

[ 分子式 ]:
C₉H₇F₃O

[ 分子量 ]:
188.146

[ 闪点 ]:
78.1±17.4 °C

[ 精确质量 ]:
188.044907

[ LogP ]:
2.61

[ 外观性状 ]:
lyophilized powder

[ 蒸汽压 ]:
0.4±0.4 mmHg at 25°C

[ 折射率 ]:
1.453

[ 储存条件 ]:
2-8°C

肌酐酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

肌酐酶文献

Analytical expression of non-steady-state concentrations and current pertaining to compounds present in the enzyme membrane of biosensor.

J. Phys. Chem. A 115(17) , 4299-306, (2011)

A mathematical model of trienzyme biosensor at an internal diffusion limitation for a non-steady-state condition has been developed. The model is based on diffusion equations containing a linear term ...

Immobilization of creatininase, creatinase and sarcosine oxidase on iron oxide nanoparticles/chitosan-g-polyaniline modified Pt electrode for detection of creatinine.

Enzyme Microb. Technol. 50(4-5) , 247-54, (2012)

Commercial enzymes, creatininase (CA) from Pseudomonas sp, creatinase (CI) from Pseudomonas sp, sarcosine oxidase (SO) from Bacillus sp were co-immobilized onto iron oxide nanoparticles/chitosan-graft...

Amperometric creatinine biosensor based on covalently coimmobilized enzymes onto carboxylated multiwalled carbon nanotubes/polyaniline composite film.

Anal. Biochem. 419(2) , 277-83, (2011)

A mixture of commercial creatinine amidohydrolase (CA), creatine amidinohydrolase (CI), and sarcosine oxidase (SO) was coimmobilized covalently via N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC...

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肌酐酶

肌酐酶用途

肌酐酶名称

肌酐酶生物活性

肌酐酶物理化学性质

肌酐酶安全信息

肌酐酶文献

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