六氟异丙醇
六氟异丙醇用途
六氟异丙醇名称
[ CAS 号 ]:
920-66-1
[ 中文名 ]:
1,1,1,3,3,3-六氟-2-丙醇
[ 英文名 ]:
Hexafluoroisopropanol
[中文别名 ]:
- 1,1,1,3,3,3六氟-2-异丙醇
- 六氟异丙醇
- 六氟异丙醇 HFIP
- 六氟异丙醇(HFIP)
- 六氟異丙醇
- 1,1,1,3,3,3-六氟-2-异丙醇
- 六氟-2-丙醇
- 1,1,1,3,3,3-六氟异丙醇
- 七氟烷相关物质C
- 1,1,1,3,3,3-六氟代-2-丙醇
[英文别名 ]:
- 2-Propanol, 1,1,1,2,3,3-hexafluoro-
- 1,1,1,2,3,3-Hexafluoropropan-2-ol
- 1,1,1,2,3,3-Hexafluoro-2-propanol
- 1,1,1,3,3,3-Hexafluoro-2-propanol
- 2-Propanol,1,1,1,3,3,3-hexafluoro-
- EINECS 213-059-4
- MFCD00011651
- Hexafluoroisopropanol
六氟异丙醇物理化学性质
[ 密度 ]:
1.5±0.1 g/cm3
[ 沸点 ]:
88.9±40.0 °C at 760 mmHg
[ 熔点 ]:
-4ºC
[ 分子式 ]:
C3H2F6O
[ 分子量 ]:
168.038
[ 闪点 ]:
7.6±27.3 °C
[ 精确质量 ]:
168.000977
[ PSA ]:
20.23000
[ LogP ]:
2.06
[ 外观性状 ]:
无色液体
[ 蒸汽压 ]:
37.2±0.3 mmHg at 25°C
[ 折射率 ]:
1.269
[ 储存条件 ]:
Store at RT.
[ 稳定性 ]:
Stable. Incompatible with strong acids, strong bases, alkali metals.
[ 水溶解性 ]:
1000 g/L (25 ºC)
六氟异丙醇MSDS
六氟异丙醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB6450000
- CHEMICAL NAME :
- 2-Propanol, 1,1,1,3,3,3-hexafluoro-
- CAS REGISTRY NUMBER :
- 920-66-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C3-H2-F6-O
- MOLECULAR WEIGHT :
- 168.05
- WISWESSER LINE NOTATION :
- FXFFYQXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1974 ppm/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Lungs, Thorax, or Respiration - dyspnea Blood - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571423
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1215,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1215,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03623 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83909 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 367 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83909 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 135 (estimated) No. of Female Employees: 113 (estimated)
六氟异丙醇安全信息
[ 符号 ]:
GHS05, GHS07, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302-H314-H361
[ 警示性声明 ]:
P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)
[ 危害码 (欧洲) ]:
C:Corrosive;
[ 风险声明 (欧洲) ]:
R20/22;R34
[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45
[ 危险品运输编码 ]:
UN 2922
[ WGK德国 ]:
2
[ RTECS号 ]:
UB6450000
[ 包装等级 ]:
II
[ 海关编码 ]:
29055910
六氟异丙醇合成路线
六氟异丙醇上下游产品
六氟异丙醇上游产品
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六氟异丙醇制备
参考生产厂家 美国杜邦公司。
六氟异丙醇海关
[ 海关编码 ]: 29055910
六氟异丙醇文献
Int. J. Pharm. 473(1-2) , 334-44, (2014)
CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the ne...
The effects of organic solvents on the membrane-induced fibrillation of human islet amyloid polypeptide and on the inhibition of the fibrillation.Biochim. Biophys. Acta 1838(12) , 3162-70, (2014)
The organic solvent dimethylsulphoxide (DMSO) and 1,1,1,3,3,3-hexafluoro-2-isopropanol (HFIP) have been widely used as a pre-treating agent of amyloid peptides and as a vehicle for water-insoluble inh...
Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration.Cells Tissues Organs 200 , 287-99, (2015)
Tissue engineering approaches in nerve regeneration search for ways to support gold standard therapy (autologous nerve grafts) and to improve results by bridging nerve defects with different kinds of ...
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