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N,N-二乙基对苯二胺

N,N-二乙基对苯二胺用途

【用途一】
用作医药中间体
【用途二】
染料中间体。作彩色相显影剂。
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N,N-二乙基对苯二胺名称

[ CAS 号 ]:
93-05-0

[ 中文名 ]:
4-氨基-N,N-二乙苯胺

[ 英文名 ]:
N,N-Diethyl-1,4-phenylenediamine

[中文别名 ]:

[英文别名 ]:

N,N-二乙基对苯二胺物理化学性质

[ 密度 ]:
0.988 g/mL at 25 °C(lit.)

[ 沸点 ]:
115-116 °C5 mm Hg(lit.)

[ 熔点 ]:
19-21 °C(lit.)

[ 分子式 ]:
C10H16N2

[ 分子量 ]:
164.24700

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
164.13100

[ PSA ]:
29.26000

[ LogP ]:
2.69620

[ 外观性状 ]:
黄色至棕色固体或液体

[ 折射率 ]:
n20/D 1.571(lit.)

[ 储存条件 ]:
Freezer

[ 稳定性 ]:
Stability Air and light sensitive. Incompatible with strong oxidizing agents, strong acids.

[ 水溶解性 ]:
<0.1 g/100 mL at 19 ºC

N,N-二乙基对苯二胺MSDS

N,N-二乙基对苯二胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SS9275000
CHEMICAL NAME :
p-Phenylenediamine, N,N-diethyl-
CAS REGISTRY NUMBER :
93-05-0
LAST UPDATED :
199712
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C10-H16-N2
MOLECULAR WEIGHT :
164.28
WISWESSER LINE NOTATION :
ZR DN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
DOSE/DURATION :
73 ug/kg
TOXIC EFFECTS :
Blood - hemorrhage Skin and Appendages - primary irritation (after topical exposure) Skin and Appendages - dermatitis, allergic (after topical exposure)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - coma
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Behavioral - muscle weakness
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Skin and Appendages - hair
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
70 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - coma
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - coma
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate increase, without fall in BP Lungs, Thorax, or Respiration - respiratory stimulation

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
2500 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990
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N,N-二乙基对苯二胺安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H314

[ 警示性声明 ]:
P280-P301 + P310-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic;

[ 风险声明 (欧洲) ]:
R25;R34

[ 安全声明 (欧洲) ]:
S26-S36-S45

[ 危险品运输编码 ]:
UN 2922 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
SS9275000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
29215190

N,N-二乙基对苯二胺合成路线

N,N-二乙基对苯二胺上下游产品

N,N-二乙基对苯二胺制备

以N,N-二乙基苯胺为原料,经亚硝化、还原、中和而得:工艺过程如下:(1)亚硝化在釜中加入150kg水,35kg N,N-二乙基苯胺和72kg盐酸,冷至0℃。在0-5℃,加入50%亚硝酸钠溶液(以100%18.5kg配成)。加毕,搅拌半小时,加入6kg食盐。搅拌2h。过滤得对亚硝基-N,N-二乙基苯胺。(2)还原、中和 在釜中加入150kg水及11kg盐酸。搅拌,加入41kg铁粉,降温至15℃,在20-25℃加亚硝基物。加毕,补加铁粉5kg,在20-25℃搅拌3h。加入碳酸钠7kg,搅拌15min,过滤。滤饼以热水洗涤。滤液和洗液中加入50kg液碱(30%),15kg食盐,静置分层。上层物料蒸馏釜,于120-150℃及真空度为8kPa减压蒸馏收集馏分,得对氨基-N,N-二乙基苯胺。

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N,N-二乙基对苯二胺海关

[ 海关编码 ]: 29215190

N,N-二乙基对苯二胺文献

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【N,N-二乙基对苯二胺】化源网提供N,N-二乙基对苯二胺CAS号93-05-0,N,N-二乙基对苯二胺MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询N,N-二乙基对苯二胺上化源网,专业又轻松。>>电脑版:N,N-二乙基对苯二胺

标题:N,N-二乙基对苯二胺_MSDS_用途_密度_CAS号【93-05-0】_化源网 地址:https://m.chemsrc.com/mip/cas/93-05-0_895845.html