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5-AIQ盐酸盐

5-AIQ盐酸盐名称

[ CAS 号 ]:
93117-07-8

[ 中文名 ]:
5-AIQ盐酸盐

[ 英文名 ]:
5-amino-2H-isoquinolin-1-one,hydrochloride

[英文别名 ]:

5-AIQ hydrochloride
5-aminoisoquinolin-1-one hydrochloride
5-Aminoisoquinolin-1(2H)-one hydrochloride
5-Aminoisoquinolinone hydrochloride

5-AIQ盐酸盐物理化学性质

[ 沸点 ]:
481ºC at 760 mmHg

[ 分子式 ]:
C₉H₉ClN₂O

[ 分子量 ]:
196.63400

[ 闪点 ]:
244.7ºC

[ 精确质量 ]:
196.04000

[ PSA ]:
59.14000

[ LogP ]:
2.90580

5-AIQ盐酸盐MSDS

5-AIQ盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933790090

5-AIQ盐酸盐合成路线

5-AIQ盐酸盐上下游产品

5-AIQ盐酸盐上游产品

5-AIQ盐酸盐下游产品

5-AIQ盐酸盐海关

[ 海关编码 ]: 2933790090

[ 中文概述 ]:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:9.0% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

5-AIQ盐酸盐文献

The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.

PLoS ONE 8(2) , e55883, (2013)

Ets-1 is a transcription factor that regulates many genes involved in cancer progression and in tumour invasion. It is a poor prognostic marker for breast, lung, colorectal and ovary carcinomas. Here,...

Inhibition of matrix metalloproteinase-2 by PARP inhibitors.

Biochem. Biophys. Res. Commun. 387 , 646-50, (2009)

Matrix metalloproteinase-2 (MMP-2), a ubiquitously expressed zinc-dependent endopeptidase, and poly(ADP-ribosyl) polymerase (PARP), a nuclear enzyme regulating DNA repair, are activated by nitroxidati...

Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.

Biochem. Biophys. Res. Commun. 350 , 1056-62, (2006)

Inhibitors of poly(ADP-ribose)polymerase (PARP), a nuclear enzyme involved in regulating cell death and cellular responses to DNA repair, show considerable promise in the treatment of cancer both in m...

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