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2-氨基-4-硝基苯酚

2-氨基-4-硝基苯酚用途

【用途一】
用作染料及医药中间体
【用途二】
用于制造活性染料、酸性染料、中性染料及溶剂染料等
【用途三】
作染料和医药的中间体。用于酸性媒性棕RH;中性黑BL、BRL、BGL等。
【用途四】
作染料和医药的中间体。用于酸性媒性棕RH;中性黑BL、BRL、BGL等
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2-氨基-4-硝基苯酚名称

[ CAS 号 ]:
99-57-0

[ 中文名 ]:
2-氨基-4-硝基苯酚

[ 英文名 ]:
2-Amino-4-nitrophenol

[中文别名 ]:

[英文别名 ]:

2-氨基-4-硝基苯酚物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
368.1±32.0 °C at 760 mmHg

[ 熔点 ]:
140-143 °C(lit.)

[ 分子式 ]:
C6H6N2O3

[ 分子量 ]:
154.123

[ 闪点 ]:
176.4±25.1 °C

[ 精确质量 ]:
154.037842

[ PSA ]:
92.07000

[ LogP ]:
1.23

[ 外观性状 ]:
橙色棱柱或黄色粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.689

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
slightly soluble

2-氨基-4-硝基苯酚MSDS

2-氨基-4-硝基苯酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SJ6300000
CHEMICAL NAME :
Phenol, 2-amino-4-nitro-
CAS REGISTRY NUMBER :
99-57-0
BEILSTEIN REFERENCE NO. :
0776533
LAST UPDATED :
199710
DATA ITEMS CITED :
25
MOLECULAR FORMULA :
C6-H6-N2-O3
MOLECULAR WEIGHT :
154.14
WISWESSER LINE NOTATION :
ZR BQ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Skin and Appendages - hair
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
246 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
143 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13750 mg/kg/15D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32500 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
13750 mg/kg/15D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
65 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
64375 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Endocrine - tumors

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
5 mg/L
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-339,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,167,1993 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,167,1993 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,167,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0280 No. of Facilities: 2232 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 20256 (estimated) No. of Female Employees: 17049 (estimated)
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2-氨基-4-硝基苯酚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R36/37/38;R40;R43;R68

[ 安全声明 (欧洲) ]:
S26-S45-S36/37/39

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
2

[ RTECS号 ]:
SJ6300000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2942000000

2-氨基-4-硝基苯酚合成路线

2-氨基-4-硝基苯酚上下游产品

2-氨基-4-硝基苯酚制备

由2,4-二硝基氯苯水解,用多硫化钠部分还原的方法制得。原料消耗定额:2,4-二硝基氯苯(工业品)2100kg/t、液碱(40%)2050kg/t、多硫化钠(100%)700kg/t、盐酸(37%)150kg/t。

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2-氨基-4-硝基苯酚海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-氨基-4-硝基苯酚文献

Mechanistic Insight into the Yolk@Shell Transformation of MnO@Silica Nanospheres Incorporating Ni(2+) Ions toward a Colloidal Hollow Nanoreactor.

Small 11(16) , 1930-8, (2015)

As an effort to develop a simple and versatile synthetic strategy that contributes to the evolution of hollow nanostructures with increasing complexity and functionality, this research is devoted to s...

Matrix-assisted laser desorption/ionization mass spectrometry using a visible laser.

Rapid Commun. Mass Spectrom. 21(24) , 4129-34, (2007)

Visible matrix-assisted laser desorption/ionization (VIS-MALDI) was performed using 2-amino-3-nitrophenol as matrix. The matrix is of near-neutral pH, and has an optical absorption band in the near-UV...

[Extraction of 2-amino-4-nitrophenol and 4-phenylphenol from aqueous solutions].

Sud. Med. Ekspert. 45(6) , 38-41, (2002)

The authors provide the results of extraction of 2-amino-4-nitrophenol and 4-phenilphenol from aqueous solutions by five organic soluvants. The dependence of the extraction degree on some factors (nat...


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