Glyurallin B

• 常用名: Glyurallin B
• 英文名: Glyurallin B
• CAS号: 199331-53-8
• 分子量: 422.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₆O₆
• 熔点: N/A
• 闪点: N/A

Glyurallin B用途

Glyurallin B是一种黄酮类化合物,可从甘草中分离得到。Glyurallin B具有清除ABTS+自由基的活性和抑制脂质过氧化的活性,EC50值分别为11.9±0.58μM和15.3±1.26μM[1]。

Glyurallin B名称

• 英文名: Glyurallin B

Glyurallin B生物活性

• 描述: Glyurallin B是一种黄酮类化合物,可从甘草中分离得到。Glyurallin B具有清除ABTS+自由基的活性和抑制脂质过氧化的活性,EC50值分别为11.9±0.58μM和15.3±1.26μM[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: Glyurallin B(10μM)对 生264.7细胞的生长具有明显的细胞毒性作用 (10微米时细胞活力为 26.3±5.3%)[1]
• 参考文献:

  [1]. Fu Y, et al. Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice. Food Chem. 2013 Nov 15;141(2):1063-71.

Glyurallin B物理化学性质

• 分子式: C₂₅H₂₆O₆
• 分子量: 422.47
• InChIKey: DPLWUTYEBRKBLI-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1cc(-c2coc3c(CC=C(C)C)c(O)cc(O)c3c2=O)cc(O)c1O

Glyurallin B靶点实验

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实验名称：Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate at 1... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4035961

实验名称：Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4035959

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4035957

实验名称：Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM incubated... 来源：ChEMBL 靶标：Nuclear factor erythroid 2-related factor 2 External Id：CHEMBL4046717

实验名称：Growth inhibition of human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4035954

实验名称：Growth inhibition of human MCF7 cells at 10 uM after 24 hrs by MTS assay relative to ... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4035952

实验名称：Growth inhibition of human SW480 cells at 10 uM after 24 hrs by MTS assay relative to... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4035953

实验名称：Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate afte... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4035962

实验名称：Inhibition of mushroom tyrosinase at 10 uM using L-tyrosine as substrate incubated fo... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL4035963

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