Tetrahedron Letters

Reductive C-alkylation of barbituric acid derivatives with carbonyl compounds in the presence of platinum and palladium catalysts

BS Jursic, DM Neumann

文献索引：Jursic, Branko S.; Neumann, Donna M. Tetrahedron Letters, 2001 , vol. 42, # 25 p. 4103 - 4107

全文：HTML全文

被引用次数: 32

摘要

Effective synthetic procedures for the preparation of mono-and di-C-alkylated barbituric acid derivatives through palladium and platinum catalytic hydrogenation of solutions of barbituric acids (unsubstituted, N-mono, and N, N′-disubstituted barbituric acids) and carbonyl compounds (aliphatic and aromatic aldehydes and ketones).