The Journal of organic chemistry

Regio-and Diastereoselective Allenylation of Aldehydes in Aqueous Media: Total Synthesis of (+)-Goniofufurone1

XH Yi, Y Meng, XG Hua, CJ Li

文献索引：Yi, Xiang-Hui; Meng, Yue; Hua, Xiao-Gang; Li, Chao-Jun Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7472 - 7480

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被引用次数: 97

摘要

The regio-and diastereoselectivities of metal-mediated allenylation of carbonyl compounds were investigated in aqueous media. Different metal mediators showed varied regioselectivities on product formation during propargylation-allenylation reactions of carbonyl compounds with simple propargyl bromide. Under the standard reaction conditions, the use of indium provided the highest regioselectivity, with a preference of ...