Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage

…, T Furukawa, T Nikai, M Niwa, Y Takaya

文献索引：Aung, Hnin Thanda; Furukawa, Tadashi; Nikai, Toshiaki; Niwa, Masatake; Takaya, Yoshiaki Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2392 - 2396

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被引用次数: 12

摘要

In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic acid (2) and 3-(3, 4-dihydroxyphenyl) lactic acid (3). In this study, we investigated the structural requirements necessary for inhibition of snake venom activity through the use of compounds, which are structurally related to rosmarinic acid (1). By ...