Identification of compounds with anti-West Nile virus activity

JR Goodell, F Puig-Basagoiti, BM Forshey…

文献索引：Goodell, John R.; Puig-Basagoiti, Francesc; Forshey, Brett M.; Shi, Pei-Yong; Ferguson, David M. Journal of Medicinal Chemistry, 2006 , vol. 49, # 6 p. 2127 - 2137

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被引用次数: 131

摘要

The lack of antiviral compounds targeting flaviviruses represents a significant problem in the development of strategies for treating West Nile Virus (WNV), Dengue, and Yellow Fever infections. Using WNV high-throughput screening techniques developed in our laboratories, we report the identification of several small molecule anti-WNV compounds belonging to four different structural classes including pyrazolines, xanthanes, acridines, and ...