Tetrahedron letters

Highly regioselective iron-promoted hydrocarboxylation of styrene

JJ Brunet, D Neibecker, RS Srivastava

文献索引：Brunet, Jean-Jacques; Neibecker, Denis; Srivastava, Radhey S. Tetrahedron Letters, 1993 , vol. 34, # 17 p. 2759 - 2762

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被引用次数: 8

摘要

Abstract The reaction of Li [HFe (CO) 4] with styrene under carbon monoxide (1 atm) in a H 2 O/iPrOH/LiOH system promotes a highly regioselective (98%) hydrocarboxylation to 2- phenylpropionic acid. In contrast, when conducted under argon, the reaction predominantly (90%) leads to 3-phenylpropionic acid.