Radical Reaction by a Combination of Phosphinic Acid and a Base in Aqueous Media.

H Yorimitsu, H Shinokubo, K Oshima

文献索引：Yorimitsu; Shinokubo; Oshima Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 2 p. 225 - 235

全文：HTML全文

被引用次数: 62

摘要

Treatment of various organic halides with phosphinic acid (hypophosphorous acid) in aqueous ethanol in the presence of a radical initiator and a base gave the corresponding reduced products in high yields. Addition of a base is indispensable for the reduction of halides by phosphinic acid. Allylic ether of o-iodophenol or 2-haloalkanal allylic acetal underwent radical cyclization under the same conditions to afford the corresponding cyclic ...