伊多塞班对甲苯磺酸盐一水化合物
更新时间：2025-08-26 11:10:20
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| 常用名 | 伊多塞班对甲苯磺酸盐一水合物 | CAS号 | 1229194-11-9 |
|---|---|---|---|
| 价格 | ￥1216.0/25mg ￥2736.0/100mg ￥606.0/10mg ￥406.0/5mg | 纯度 | 98.0% |
| 备货期 | 2天 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke preventionIC50 Value:Target: factor XaEdoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammatory drugs for concurrent illnesses[1].in vitro: Edoxaban PK was not affected by concomitant low-dose ASA or naproxen, but high-dose ASA increased systemic exposure of edoxaban by approximately 30%. The effects of edoxaban on prothrombin time, activated partial thromboplastin time, international normalized ratio, anti-FXa, and intrinsic FXa activity were not influenced by administration with ASA or naproxen. Inhibition of platelet aggregation by high-dose ASA, low-dose ASA, or naproxen was not affected by edoxaban[1].in vivo: Forty-eight subjects, aged 18 to 45 years, received either edoxaban 60 mg once daily × 7 days (n = 24) or digoxin 0.25 mg twice daily × 2 days and once daily × 5 days (n = 24) and then concomitantly for 7 days. Serial blood and urine samples were collected for digoxin and edoxaban concentrations on days 7 and 14. Serial coagulation assays were measured for edoxaban on days 7 and 14. Edoxaban PK parameters demonstrated mild increases in area under the curve and peak concentrations of 9.5% and 15.6%, respectively[2],Clinical trial: Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans was reported[3]. 物理化学性质： CAS号：1229194-11-9 常用中文名：伊多塞班对甲苯磺酸盐一水合物 常用英文名：Edoxaban tosylate monohydrate 分子式：C31H40ClN7O8S2 分子量：738.274 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20℃ |
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：依多沙班对甲苯磺酸盐一水合物
- 价格： ￥576.9/100mg ￥115.9/10mg ￥4553.9/1g ￥1297.9/250mg
- 纯度：97.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：伊多塞班对甲苯磺酸盐一水化合物
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：N1-(5-氯吡啶-2-基)-N2-((1S,2R,4S)-4-(二甲基甲酰胺基)-2-(5-甲基-4,5,6,7-四氢噻唑并[5,4-c]吡啶-2-甲酰胺基)环己基)草酰胺4-甲基苯磺酸盐一水合物
- 价格： ￥需询单/100mg ￥需询单/250mg ￥需询单/50mg
- 纯度：99.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：伊多塞班对甲苯磺酸盐一水化合物
- 价格： ￥1216.0/25mg ￥2736.0/100mg ￥606.0/10mg ￥406.0/5mg
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
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参考价格：￥312/5mg