伊多塞班对甲苯磺酸盐一水合物

更新时间：2024-01-02 17:50:18

伊多塞班对甲苯磺酸盐一水合物结构式	常用名	伊多塞班对甲苯磺酸盐一水合物	英文名	Edoxaban tosylate monohydrate
	CAS号	1229194-11-9	分子量	738.274
	密度	N/A	沸点	N/A
	分子式	C₃₁H₄₀ClN₇O₈S₂	熔点	N/A
	MSDS	N/A	闪点	N/A

伊多塞班对甲苯磺酸盐一水合物用途

Edoxaban(DU-176)是口服的FXa抑制剂。

中文名	甲磺酸依度沙班
英文名	edoxaban tosylate hydrate
中文别名	伊多塞班对甲苯磺酸盐一水合物
英文别名	更多

描述	Edoxaban(DU-176)是口服的FXa抑制剂。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> 因子Xa 研究领域 >> 心血管疾病
参考文献	[1]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. [Epub ahead of print] [2]. Mendell J, Noveck RJ, Shi M. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination. J Cardiovasc Pharmacol. 2012 Oct;60(4):335-41. [3]. Bathala MS, Masumoto H, Oguma T, Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012 Dec;40(12):2250-5.

描述

Edoxaban(DU-176)是口服的FXa抑制剂。

相关类别

信号通路 >> 代谢酶/蛋白酶 >> 因子Xa

研究领域 >> 心血管疾病

参考文献

[1]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. [Epub ahead of print]

[2]. Mendell J, Noveck RJ, Shi M. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination. J Cardiovasc Pharmacol. 2012 Oct;60(4):335-41.

[3]. Bathala MS, Masumoto H, Oguma T, Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012 Dec;40(12):2250-5.

分子式	C₃₁H₄₀ClN₇O₈S₂
分子量	738.274
精确质量	737.206848
PSA	236.85000
LogP	4.34050
外观性状	白色至类白色粉末
储存条件	-20℃

N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide,4-methylbenzenesulfonic acid,hydrate

Edoxaban tosylate monohydrate

N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl]ethanediamide 4-methylbenzenesulfonate hydrate (1:1:1)

Edoxaban tosilate monohydrate

Edoxaban tosilate hydrate (JAN)

Edoxaban

Lixiana

Edoxaban tosilate

LIXIANA (TN)

CS-1333

Ethanediamide, N-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonat e, hydrate (1:1:1)

Edoxaban Impurity 1

Edoxaban (tosylate monohydrate)