常用名 | Thiocolchicine | CAS号 | 2730-71-4 |
---|---|---|---|
价格 | $需询单/100mg $需询单/250mg $需询单/500mg | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-Thiocolchicine.html |
产品详情(用途,包装等)
Thiocolchicine is a potent tubulin polymerization and microtubule assembly inhibitor, a axonal cytoskeleton modulator and apoptosis inducer. Structurally, thiocolchicine is a colchicine analog in which the C-10 methoxy is replaced with a thiomethyl moiety. Thiocolchicine was shown to bind with high affinity to the colchicine site on tubulin (Ka = 1.07 +/- 0.14 x 10(6) M-1). Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors. |