Orotic acid
更新时间：2021-07-26 18:31:53
采购访问：39次
| 常用名 | 乳清酸 | CAS号 | 65-86-1 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Orotic acid (OA) is an intermediate in pyrimidine metabolism.IC50 Value: Target: Nucleoside antimetabolite/analogin vitro: OA increases cell proliferation and decreases apoptosis in serum-starved SK-Hep1 hepatocellular carcinoma cells, which may ascribe to the inhibition of AMP-activated protein kinase (AMPK) phosphorylation and thus activation of mammalian target of rapamycin complex 1 (mTORC1) [1].in vivo: male Fischer 344 rats (130-150 g) to two-thirds PH in the absence or in the presence of OA (a 300-mg tablet of OA methyl ester implanted intraperitoneally at the time of two-thirds PH). treatment with OA resulted in a near-100% inhibition of RNR induced by two-thirds PH in rat liver, as monitored by enzyme activity and protein level [2]. The increases of hepatic OA and betaine levels in OA feeding rats was also found when compared to the normal rats [3]. Feeding 1% OA with diet decreased the phosphorylation of AMPK and increased the maturation of SREBP-1 and the expression of SREBP-responsive genes in the rat liver. OA-induced lipid accumulation was also completely inhibited by rapamycin. Mouse hepatocytes and mice were resistant to OA-induced lipogenesis because of little if any response in AMPK and downstream effectors [4]. 物理化学性质： CAS号：65-86-1 常用中文名：乳清酸 常用英文名：Orotic acid 分子式：C5H4N2O4 分子量：156.096 密度：1.8±0.1 g/cm3 沸点：656.9±65.0 °C at 760 mmHg 熔点：>300°C 闪点：351.1±34.3 °C 储存条件：室温 |
达阳化工（杭州）有限公司
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主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 成都百事兴科技实业有限公司
- 四川省 成都市 蒲江县
- 产品名：乳清酸(无水)(Orotic acid)
- 价格： ￥需询单/1kg ￥需询单/10kg ￥需询单/500kg ￥需询单/1ton
- 纯度：99.0%
- 备货期：需询单
- 联系人：谢运棋副总
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：乳清酸
- 价格： ￥29.9/25g ￥288.9/500g ￥205.9/1ml ￥72.9/100g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$66/10mM*1mLinDMSO