| 常用名 | MIRK-IN-1 | CAS号 | 1386979-55-0 |
|---|---|---|---|
| 价格 | ¥5910.0/50mg ¥1477.0/10mg ¥需询单/1g ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/T288016.html | ||
| 产品详情(用途,包装等)
用途: Mirk-IN-1 is a potent inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A with IC50 of 68±48 nM and 22±8 nM respectively.IC50 value: 68±48/22±8 nM (Dyrk1B/Dyrk1A) [1]Target: Dyrk inhibitorMirk-IN-1 had an EC50 of 1.9 ±0.2 mmol/L on SW620 cells. At a much higher concentration of 10 mmol/L in a kinase assay, Mirk-IN-1 inhibited the activities of DYRK1A, ABL, FLT3, and MARK1 by88%, 64%, 56%, and 73%, respectively [1]. Mirk-IN-1 was able to block tumor cells from undergoing reversible arrest in a quiescent G0 state and enable some cells to exit quiescence [2]. 物理化学性质: CAS号:1386979-55-0 常用中文名:MIRK-IN-1 常用英文名:TC-S 7004 分子式:C23H17Cl2N5O4 分子量:498.318 密度:1.5±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |