白头翁皂苷D
更新时间：2025-08-29 16:24:31
采购访问：32次
| 常用名 | 白头翁皂苷 D | CAS号 | 68027-15-6 |
|---|---|---|---|
| 价格 | ￥2031.0/5mg ￥需询单/1g ￥需询单/1g ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/P342584.html | ||
| 产品详情（用途，包装等）
用途： Pulsatilla saponin D(SB365) isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer.IC50 value:Target:SB365 effectively inhibited the growth of gastric cancer cells. Its apoptotic effect was accompanied by increased evidence of cleaved caspase-3 and poly(ADP ribose) polymerase. To elucidate the anticancer mechanism of SB365, we used an array of 42 different receptor tyrosine kinases (RTKs). Of the 42 different phospho-RTKs, SB365 strongly inhibited expression of activated c-mesenchymal-epithelial transition factor (c-Met) in gastric cancer cells [1]. SB365 strongly suppressed the growth and proliferation of 5 human pancreatic cancer cell lines (MIAPaCa-2, BXPC-3, PANC-1, AsPC-1 and HPAC). The apoptotic effect of SB365 was demonstrated by increased levels of cleaved caspase-3 and decreased Bcl-2 expression via mitochondrial membrane potential, as well as elevated numbers of terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling (TUNEL)-positive apoptotic cells [2]. SB365 strongly suppressed the growth and proliferation of colon cancer cells and induced their apoptosis. Also, SB365 showed anti-angiogenic activity by decreasing the expression of HIF-1α and VEGF. These results were confirmed by an in vivo study showing that SB365 significantly inhibited tumor growth by the induction of apoptosis and inhibition of angiogenesis with stronger anticancer activity than 5-FU [3]. 物理化学性质： CAS号：68027-15-6 常用中文名：白头翁皂苷 D 常用英文名：Pulsatilla saponin D 分子式：C47H76O17 分子量：913.096 密度：1.4±0.1 g/cm3 沸点：997.6±65.0 °C at 760 mmHg 熔点：N/A 闪点：285.4±27.8 °C 储存条件：-20°C |
上海阿拉丁生化科技股份有限公司
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地区： 上海市 上海市 浦东新区
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主要合作伙伴：
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：常春藤皂苷元3-O-α-L-吡喃鼠李糖-(1→2)-β-D-吡喃葡萄糖-(1→4)-α-L-吡喃阿拉伯糖苷
- 价格：
- 纯度：96.0%
- 备货期：10天
- 联系人：徐经理
- 四川恒诚致远生物科技有限公司
- 四川省 成都市 温江区
- 产品名：白头翁皂苷D
- 价格： ￥需询单/5mg ￥需询单/20mg ￥需询单/100mg ￥需询单/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：张半夏
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：白头翁皂苷D
- 价格： ￥2031.0/5mg ￥需询单/1g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$627/10mM*1mLinDMSO