| 常用名 | 葡糖硫金 | CAS号 | 12192-57-3 |
|---|---|---|---|
| 价格 | ¥899.0/5mg ¥3999.0/100mg ¥需询单/1g ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/A350929.html | ||
| 产品详情(用途,包装等)
用途: Aurothioglucose (Gold thioglucose) is a well known active-site inhibitor of TrxR1, inhibited TrxR1 activity in HeLa cell cytosol but had no effect on the viability of the cells.IC50 value:Target: TrxR1in vitro: Trx1 redox state and ROS generation were measured in cells exposed to the TrxR1 inhibitors aurothioglucose (ATG) and monomethylarsonous acid (MMA(III)) and in cells depleted of TrxR1 activity by siRNA knock down [1].in vivo: Adult mice received a single intratracheal dose of 0.375 μg/g lipopolysaccharide (LPS) 12 h before a single intraperitoneal injection of 25 mg/kg ATG. Control mice received intratracheal and/or intraperitoneal saline. ATG treatment significantly attenuated lung injury, increased lung GCLM expression and GSH levels, and decreased mortality. GSH depletion completely prevented the protective effects of ATG in LPS/hyperoxia-exposed mice [2]. 物理化学性质: CAS号:12192-57-3 常用中文名:葡糖硫金 常用英文名:Aurothioglucose 分子式:C6H11AuO5S 分子量:392.18000 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:通风低温干燥 |