| 常用名 | ABT-046 | CAS号 | 1031336-60-3 |
|---|---|---|---|
| 价格 | ¥1754.0/5mg ¥14270.0/10mg ¥需询单/1g ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/A126383.html | ||
| 产品详情(用途,包装等)
用途: ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50= 8 nM).IC50 value: 8 nM [1]Target: DGAT-1Oral administration at doses ≥0.03 mg/kg significantly reduced postprandial triglycerides in mice following an oral lipid challenge. Further assessment in both acute and chronic safety pharmacology and toxicology studies demonstrated a clean profile up to high plasma levels, thus culminating in the nomination of 14 as clinical candidate ABT-046. 物理化学性质: CAS号:1031336-60-3 常用中文名:ABT-046 常用英文名:ABT-046 分子式:C20H22N4O2 分子量:350.41400 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |