| 常用名 | GSK269962A hydrochloride | CAS号 | 2095432-71-4 |
|---|---|---|---|
| 价格 | ¥需询单/1g | 纯度 | 98.9% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情(用途,包装等)
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. GSK 269962 could reverse corticosterone-induced depressive-like behaviour and changes in cystometric parameters associated with detrusor overactivity, as well as undo the alterations of several biomarkers related to both disorders (i.e., pro-inflammatory/anti-inflammatory cytokines and neurotrophins) in serum, urinary bladder, and different brain structures. |