| 常用名 | HPK1-IN-7 | CAS号 | 2320462-65-3 |
|---|---|---|---|
| 价格 | ¥需询单/1g | 纯度 | 98.9% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情(用途,包装等)
HPK1-IN-7 is a potent, orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) inhibitor (IC50=2.6 nM) with excellent family and kinome selectivity. HPK1-IN-7 shows selectivity against IRAK4 (59 nM) and GLK (140 nM). HPK1-IN-7 shows robust efficacy against MC38 syngeneic tumor model in combination with anti-PD1. |