| 常用名 | 托彻普 | CAS号 | 262352-17-0 |
|---|---|---|---|
| 价格 | ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Torcetrapib(CP-529414) is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma.IC50 value: 37 nM [1]Target: CETP inhibitorin vitro: Torcetrapib dose-dependently increases aldosterone release from H295R cells after either 24 or 48 h of treatment with an EC50 of approximately 80 nM, this effect is mediated by calcium channel as calcium channel blockers completely blocks torcetrapib-induced corticoid release and calcium increase. Torcetrapib (1 μM) significantly increases the expression of steroidogenic gene, CYP11B2 and CYP11B1, in H295R cell lines [2].in vivo: Torcetrapib ( 物理化学性质: CAS号:262352-17-0 常用中文名:托彻普 常用英文名:Torcetrapib 分子式:C26H25F9N2O4 分子量:600.47 密度:1.4±0.1 g/cm3 沸点:504.8±50.0 °C at 760 mmHg 熔点:54-58ºC 闪点:259.1±30.1 °C 储存条件:Store at RT |