澳洲茄边碱
更新时间：2024-05-08 09:53:39
| 常用名 | 澳洲茄边碱 | CAS号 | 20311-51-7 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells. IC50 value:Target: Anticancer natural compoundin vitro: Solamargine reduced HepG2 cell viability in a concentration-dependent manner. At 7.5μM solamargine decreased cell viability by less than 20% in HepG2 cells. At the highest dose, solamargine decreased cell migration and invasion by more than 70% and 72% in HepG2 cells, respectively. Western blotting and gelatin zymography results showed that solamargine reduced expression and function of MMP-2 and MMP-9 proteins [1]. SM increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) in a time-dependent fashion. SM also inhibited phosphorylation and protein expression of signal transducer and activator of transcription 3 (Stat3), a transcription factor, which was abrogated by the SB203580, a specific inhibitor of p38 MAPK. In addition, SM induced protein expression of p21, one of cyclin-dependent kinase inhibitors, and this was not observed in cell overexpression of Stat3 or cells treated with SB203580 [2]. SM significantly inhibited the growth of SMMC-7721 and HepG2 cells and induced cell apoptosis. Cell cycle analysis revealed that SM caused cell cycle arrest at the G2/M phase. Moreover, SM could up-regulate the expression of caspase-3 [3]. 物理化学性质： CAS号：20311-51-7 常用中文名：澳洲茄边碱 常用英文名：Solamargine 分子式：C45H73NO15 分子量：868.059 密度：1.4±0.1 g/cm3 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C |
- 云南西力生物技术股份有限公司
- 云南省 昆明市 盘龙区
- 产品名：澳洲茄边碱
- 价格： ￥需询单/5mg
- 纯度：98.0%
- 备货期：10天
- 联系人：郑雪平
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：澳洲茄边碱
- 价格： ￥5149.9/100mg ￥154.9/1mg ￥1441.9/25mg ￥411.9/5mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 四川恒诚致远生物科技有限公司
- 四川省 成都市 温江区
- 产品名：澳洲茄边碱
- 价格： ￥需询单/5mg ￥需询单/20mg ￥需询单/100mg ￥需询单/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：张半夏
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：澳洲茄边碱
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：澳洲茄边碱
- 价格： ￥938.0/20mg
- 纯度：98.0%
- 备货期：1天
- 联系人：刘佳
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参考价格：$206/10mM*1mLinDMSO