| 常用名 | BC-1382 | CAS号 | 1013753-99-5 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: A potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction with IC50 of 5 nM; drastically increases PIAS1 protein level with IC50 of 100 nM and improves PIAS1 protein stability, with no effect on PIAS3, PIAS4, and HECTD2 protein levels; suppresses LPS-induced PIAS1 degradation and restores PIAS1 protein levels at 800 nM, and proinflammatory cytokines released by PBMCs; attenuates LPS- and Pseudomonas aeruginosa-induced lung inflammation 物理化学性质: CAS号:1013753-99-5 常用中文名:BC-1382 常用英文名:BC-1382 分子式:C23H29N3O5S 分子量:459.559 密度:1.3±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8°C,密封,干燥 |