| 常用名 | JGB1741 | CAS号 | 1256375-38-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ∼15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research[1]. 物理化学性质: CAS号:1256375-38-8 常用中文名:JGB1741 常用英文名:JGB1741 分子式:C27H24N2O2S 分子量:440.56 密度:1.3±0.1 g/cm3 沸点:700.2±60.0 °C at 760 mmHg 熔点:N/A 闪点:377.3±32.9 °C 储存条件:2-8°C,密封,干燥 |