Noscapine
更新时间：2024-07-15 12:31:15
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| 常用名 | 那可丁 | CAS号 | 128-62-1 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Noscapine is an orally administrable drug used worldwide for cough suppression, primarily mediated by its σ-receptor agonist activity, and possess anticancer activity.Target: σ-receptorin vitro: Noscapine is a phthalideisoquinoline alkaloid from opium, is a recently discovered anticancer drug and is currently under investigation in phase-I/II clinical trials for the treatment of leukemia and lymphoma. Noscapine causes few or no side effects and has been widely used as a cough suppressant in developing countries. Noscapine has been demonstrated to interact with microtubules. Interestingly, unlike many other microtubule-targeting agents such as Paclitaxel and Nocodazole, Noscapine does not obviously affect the total amount of microtubule polymers in cells; instead, it significantly increases the time microtubules spend in the pause state. The alteration of microtubule dynamics then activates the spindle checkpoint and arrests cell cycle progression at mitosis, leading to apoptotic cell death. 物理化学性质： CAS号：128-62-1 常用中文名：那可丁 常用英文名：Noscapine 分子式：C22H23NO7 分子量：413.421 密度：1.3±0.1 g/cm3 沸点：565.3±50.0 °C at 760 mmHg 熔点：174-176ºC 闪点：295.7±30.1 °C 储存条件：-20℃ |
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Noscapine
- 价格： ￥259.0/50mg ￥961.0/10mg ￥需询单/1g ￥需询单/1g
- 纯度：97.0%
- 备货期：1天
- 联系人：阿拉丁
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：Noscapine
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
351666998
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参考价格：$66/10mM*1mLinDMSO