| 常用名 | BRD3308 | CAS号 | 1550053-02-5 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM, displays >20-fold selectivity over HDAC1 and HDAC2, >500-fold selectivity over other HDAC isoforms; attenuates PE-mediated phosphorylation of ERK, but not JNK; also activates HIV-1 transcription in the 2D10 cell line, induces outgrowth of HIV-1 from resting CD4+ T cells isolated from antiretroviral-treated, aviremic HIV+ patients ex vivo and disrupts HIV-1 latency; suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. 物理化学性质: CAS号:1550053-02-5 常用中文名:BRD3308 常用英文名:BRD3308 分子式:C15H14FN3O2 分子量:287.289 密度:1.4±0.1 g/cm3 沸点:449.9±45.0 °C at 760 mmHg 熔点:N/A 闪点:225.9±28.7 °C 储存条件:-20°C,密闭,干燥 |