| 常用名 | SRS16-86 | CAS号 | 1793052-96-6 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: SRS16-86 is an inhibitor of ferroptosis. It inhibits ferroptosis induced by erastin in HT-1080 and NIH3T3 cells. SRS16-86 prevents renal tubular damage and increases in serum levels of urea and creatine in a mouse model of renal ischemia-reperfusion injury (IRI). In a rat model of spinal cord injury, SRS16-86 increases the levels of glutathione peroxidase 4 (GPX4), system xc- cystine/glutamate transporter (xCT), and glutathione (GSH) and decreases levels of IL-1β, TNF-α, ICAM-1, and the lipid peroxidation marker 4-hydroxy nonenal (4HNE) in injured spinal cord epicenters. It also increases tissue sparing and improves locomotor recovery in the same model. 物理化学性质: CAS号:1793052-96-6 常用中文名:SRS16-86 常用英文名:SRS16-86 分子式:C26H32N4O2 分子量:432.558 密度:1.3±0.1 g/cm3 沸点:614.9±55.0 °C at 760 mmHg 熔点:N/A 闪点:325.7±31.5 °C |