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5-羟基-4,7-二甲氧基黄酮

更新时间:2024-07-15 12:35:32 采购访问:22次

常用名 5-羟基-4’,7-二甲氧基黄酮 CAS号 5128-44-9
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines.And it also showed inhibition of the drug efflux pumps (with IC50 = 51.64 μg/ml).IC50:51.64 μg/ml(Candida albicans drug efflux pumps)[2]In vitro: The isolated 7,4'-Di-O-methylapigenin was further investigated for its inhibitory activity on ABC drug efflux pumps in C. albicans by monitoring an increase in ciprofloxacin, assessing the level of its accumulation, in response to reserpine. There was a higher accumulation of ciprofloxacin in Candida cells in the presence of 7,4'-Di-O-methylapigenin than with reserpine. The compound 7,4'-Di-O-methylapigenine demonstrated the activity in a dose-dependent manner with IC50 value of 51.64 μg/ml. These results support those obtained from synergism assays where by the underlying synergistic antifungal mechanisms could be due to blockage of ABC efflux pumps and increasing the susceptibility of Candida to miconazole.[2]In vivo: In searching for natural products as potential anti-inflammatory agents, 7,4'-Di-O-methylapigenin wasn't evaluated in vivo for its ability to inhibit acute inflammation.[1]
物理化学性质:
CAS号:5128-44-9
常用中文名:5-羟基-4’,7-二甲氧基黄酮
常用英文名:7,4'-Di-O-methylapigenin
分子式:C17H14O5
分子量:298.290
密度:1.3±0.1 g/cm3
沸点:515.2±50.0 °C at 760 mmHg
熔点:N/A
闪点:193.3±23.6 °C
储存条件:-20℃

供应商信息

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参考价格:¥1964/1g
其他供应商价格:
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2022-03-04 芹菜素二甲醚
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2025-09-17 5-羟基-4,7-二甲氧基黄酮
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2025-12-29 芹菜素二甲醚
价格:¥需询单
2016-03-31 5-羟基-4,7-二甲氧基黄酮
价格:¥2500.0
2018-03-25 芹菜素二甲醚
价格:¥需询单

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