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Moxonidine hydrochloride

更新时间:2024-07-15 12:36:41 采购访问:19次

常用名 盐酸莫索尼定 CAS号 75536-04-8
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.Target: I1-RMoxonidine Hydrochloride is a centrally acting antihypertensive agent. Mixed Nischarin (I1 imidazoline receptor) and α2-AR (adrenergic) agonist; displays 40-fold higher affinity for I1 receptors versus α2-adrenoceptors. Moxonidine reduced stimulated NE overflow (log EC50: -6.15 +/- 0.14). AGN192403, a selective ligand at I1-R, had no influence on the dose-response curve of moxonidine (log EC50: -6.01 +/- 0.25) [1]. The hypotensive and bradycardic actions of moxonidine but not clonidine are mediated through imidazoline receptors and are dependent on intact noradrenergic pathways within the RVLM. Furthermore, the noradrenergic innervation may be associated with a 42 kDa imidazoline receptor protein [2].
物理化学性质:
CAS号:75536-04-8
常用中文名:盐酸莫索尼定
常用英文名:Moxonidine hydrochloride
分子式:C9H13Cl2N5O
分子量:278.138
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

上海念兴实业有限公司 认证供应商

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参考价格:$96/10mg
其他供应商价格:
2022-03-04 盐酸莫索尼定
价格:¥1938.0
2021-02-06 Moxonidine hydrochloride
价格:¥4625.0

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