9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺
更新时间：2024-07-15 12:36:52
采购访问：15次
| 常用名 | 依匹斯汀 | CAS号 | 80012-43-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.Target: Histamine ReceptorEpinastine shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. Epinastine inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs [1]. Epinastine is able to displace specific [3H]NC-5Z binding at low concentrations in the locust nervous tissue. Epinastine binds to the honey bees neuronal octopamine receptor with Ki of 1.1 nM. Epinastine antagonises octopamine-induced cAMP formation in the insect brain [2]. Epinastine causes an inhibition of histamine release from rat peritoneal mast cells induced by both antigen-antibody reaction and compound 48/80. Epinastine is similarly effective in inhibiting compound 48/80-induced histamine release not only from isolated rat peritoneal mast cells but also from rat mesenterial pieces. Epinastine is effective in inhibiting not only Ca2+ uptake into lung mast cells in actively sensitized guinea pigs but also Ca2+ release from the intracellular Ca store of rat peritoneal mast cells exposed to both compound 48/80 and substance P [3]. Epinastine shows a dose- and time-dependent suppressive effect on IL-8, one of the chemokines for eosinophils, released from eosinophils isolated from atopic diseases [4]. 物理化学性质： CAS号：80012-43-7 常用中文名：依匹斯汀 常用英文名：Epinastine 分子式：C16H15N3 分子量：249.31000 密度：1.32 g/cm3 沸点：428ºC at 760 mmHg 熔点：270ºC 闪点：212.7ºC 储存条件：2-8℃ |
上海念兴实业有限公司
认证状态：已认证供应商
商品数：403768件
电话：18916513247
地址：2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区： 上海市 上海市 普陀区
联系人：小陈
联系人电话：0086-021-52280163
邮件：sales@echemcloud.com
网址：http://www.echemcloud.com
主要市场：
年贸易额：
外贸占销售比例：
主要合作伙伴：
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Epinastine
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：9,13B-二氢-1H-二苯并[c,f]咪唑并[1,5-a]氮杂卓-3-胺
- 价格： ￥需询单/100mg ￥需询单/1g ￥需询单/250mg ￥需询单/50mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
查看所有供应商和价格请点击：
参考价格：$106/10mM*1mLinDMSO