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三七皂苷R1

更新时间:2024-07-15 12:36:53 采购访问:25次

常用名 三七皂苷R1 CAS号 80418-24-2
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Notoginsenoside R1, the main bioactive component in panaxnotoginseng, is reported to have some neuronal protective, antihypertensive effects. IC50 value:Target:In vitro:In vivo: Notoginsenoside R1 significantly reduce blood pressure in spontaneously hypertensive rats and induce nitric oxide generation through increasing the phosphorylation of iNOS. Notoginsenoside R1 reduces the caudal blood pressure of spontaneously hypertensive rats through induction of iNOS regulated by long non-coding RNA AK094457 [1]. The mice with notoginsenoside R1 treatment showed significant amelioration in the cognitive function and increased choline acetyl transferase expression, as compared to the vehicle treated mice. Notoginsenoside R1 treatment inhibited Aβ accumulation and increased insulin degrading enzyme expression in both APP/PS1 mice and N2a-APP695sw cells [2]. In Notoginsenoside R1 treated rats, expression of TGF-β1and Smad3 at each time point was down-regulated, with statistical significance(P0.05) compared with that in the NDMA group [3].
物理化学性质:
CAS号:80418-24-2
常用中文名:三七皂苷R1
常用英文名:Notoginsenoside R1
分子式:C47H80O18
分子量:933.127
密度:1.4±0.1 g/cm3
沸点:1010.5±65.0 °C at 760 mmHg
熔点:218 °C
闪点:564.9±34.3 °C
储存条件:2-8°C

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参考价格:$111/10mM*1mLinDMSO
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