| 常用名 | H3B-8800 | CAS号 | 1825302-42-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.21% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: H3B-8800 is an orally available splicing modulator that targets spliceosome SF3b complex containing either WTor mutant SF3B1 (binding IC50 of 0.3-2 nM); demonstrates dose-dependent inhibition of both canonical splicing and aberrant splicing induced by mutant SF3B1 in in vitro assays of biochemical splicing, induces lethality in spliceosome-mutant cancer cells. Blood Cancer Phase 1 Clinical 物理化学性质: CAS号:1825302-42-8 常用中文名:H3B-8800 常用英文名:H3B-8800 分子式:C31H45N3O6 分子量:555.706 密度:1.2±0.1 g/cm3 沸点:710.6±60.0 °C at 760 mmHg 熔点:N/A 闪点:383.6±32.9 °C |