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地诺孕素

更新时间:2025-08-21 16:23:58 采购访问:63次

常用名 地诺孕素 CAS号 65928-58-7
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Target: progesterone receptor agonistDienogest is an orally active synthetic progesterone (or progestin). It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinylated progestin which is structurally related to testosterone [1]. Complete sperm suppression was observed in rats sacrificed either 60 or 90 days after dienogest (DNG)+ testosterone undecanoate (TU) administration, for two injections at 45-day interval. The neutral α-glucosidase activity in these treated rats remained in the normal range. Germ cell loss due to apoptosis was frequently observed both after 60 or 90 days of combination treatment. Significant decline in serum gonadotropin and testosterone, both serum and intratesticular levels, were observed in the treated rats. Following stoppage of treatment (given at 45-day interval) after two (0 and 45 days) or three injections (0, 45 and 90 days), complete restoration of spermatogenesis was observed by 120 and 165 days, respectively [2].Clinical indications: Adenomyosis; EndometriosisFDA Approved Date: 1995 Toxicity: weight gain; increased blood pressure; breast tenderness and nausea
物理化学性质:
CAS号:65928-58-7
常用中文名:地诺孕素
常用英文名:Dienogest
分子式:C20H25NO2
分子量:311.418
密度:1.2±0.1 g/cm3
沸点:549.0±50.0 °C at 760 mmHg
熔点:210-214ºC
闪点:285.8±30.1 °C
储存条件:-20°C Freezer

供应商信息

上海化源世纪贸易有限公司 认证供应商

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参考价格:$106/10mM*1mLinDMSO
其他供应商价格:
2018-03-26 地诺孕素
价格:¥需询单
2022-08-16 地诺孕素
价格:¥25000.0
2018-03-05 地诺孕素
价格:¥需询单
2017-09-11 地诺孕素
价格:¥需询单
2022-03-22 Dienogestrel
价格:$需询单
2021-02-06 Dienogest
价格:¥1789.0
2024-01-09 Dienogestrel
价格:$需询单

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