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Bavisant dihydrochloride?

更新时间:2025-09-15 18:39:39 采购访问:19次

常用名 Bavisant dihydrochloride CAS号 929622-09-3
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Bavisant Hcl (JNJ-31001074) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. IC50 Value: Target: H3 receptorin vitro: Bavisant completed a phase II ADHD trial, but no results have been reported [1].in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1?mg/day, 3?mg/day and 10?mg/day groups, respectively; the change in the 10?mg/day group was not statistically superior to placebo (p=0.161), and hence statistical comparisons of the 1?mg/day and 3?mg/day groups with placebo based on a step-down closed testing procedure were not performed [2].Clinical trial: A Study to Characterize the Pharmacokinetics and Effect of Food on JNJ-31001074 in Healthy Volunteers. Phase 2
物理化学性质:
CAS号:929622-09-3
常用中文名:Bavisant dihydrochloride
常用英文名:Bavisant (dihydrochloride)
分子式:C19H29Cl2N3O2
分子量:402.35800
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

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上海化源世纪贸易有限公司 认证供应商

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参考价格:$240/5mg
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