Bavisant dihydrochloride

• 常用名: Bavisant dihydrochloride
• 英文名: Bavisant (dihydrochloride)
• CAS号: 929622-09-3
• 分子量: 402.35800
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₉Cl₂N₃O₂
• 熔点: N/A
• 闪点: N/A

Bavisant dihydrochloride用途

Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。

Bavisant dihydrochloride名称

• 中文名: Bavisant dihydrochloride
• 英文名: (4-cyclopropylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone,dihydrochloride

Bavisant dihydrochloride生物活性

• 描述: Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
  信号通路 >> 免疫及炎症 >> 组胺受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Robert L. Hudkins, Rita Raddatz, Ming Tao, Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist. J. Med. Chem. 2011, 54

  [2]. Weisler RH, Pandina GJ, Daly EJ, Randomized clinical study of a histamine H3 receptor antagonist for the treatment of adults with attention-deficit hyperactivity disorder. CNS Drugs. 2012 May 1;26(5):421-34.

Bavisant dihydrochloride物理化学性质

• 分子式: C₁₉H₂₉Cl₂N₃O₂
• 分子量: 402.35800
• 精确质量: 401.16400
• PSA: 36.02000
• LogP: 2.85670
• InChIKey: PBVFXCXXVLBYKF-UHFFFAOYSA-N
• SMILES: Cl.Cl.O=C(c1ccc(CN2CCOCC2)cc1)N1CCN(C2CC2)CC1
• 储存条件: 2-8℃

Bavisant dihydrochloride靶点实验

查看更多实验

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

共3条，当前第1页，共1页

1

Bavisant dihydrochloride英文别名

• UNII-1B5560RN9F
• Bavisant dihydrochloride
• Bavisant dihydrochloride anhydrous
• Bavisant (dihydrochloride)