替韦立马
更新时间：2026-03-11 15:06:54
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| 常用名 | Tecovirimat | CAS号 | 869572-92-9 |
|---|---|---|---|
| 价格 | ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg | 纯度 | 0.0% |
| 备货期 | 需询单 | 库存 | 有现货 |
| 产品详情（用途，包装等）
用途： Tecovirimat(ST-246) is an orally bioavailable antipoxvirus compound; potent and selective active against multiple orthopoxviruses with EC50 about 10 nM.IC50 value: 10 nM [1]Target: antipoxvirusin vitro: ST-246 targets the cowpox virus V061 gene, which encodes a major envelope protein homologous to the vaccinia virus F13L gene product. The antiviral potency and selectivity of ST-246 was measured in CPE assays against a panel of DNA- and RNA-containing viruses. In these assays, the EC50 for inhibition of vaccinia virus was determined to be 0.01 μM, while the EC50 values for inhibition of unrelated viruses were >40 μM [1]. ST-246 was evaluated for activity against cowpox virus (CV), vaccinia virus (VV), and ectromelia virus (ECTV) and had an in vitro 50% effective concentration (EC50) of 0.48 microM against CV, 0.05 microM against VV, and 0.07 microM against ECTV. The selectivity indices were >208 and >2,000 for CV and VV, respectively. The in vitro antiviral activity of ST-246 was significantly greater than that of cidofovir, which had an EC50 of 41.1 microM against CV and 29.2 microM against VV, with selectivity indices of >7 and >10, respectively [2]. in vivo: Mice were treated with placebo (vehicle), ST-246 administered by oral gavage at 50 mg/kg twice a day (b.i.d.) for 14 days, or CDV administered as a single intraperitoneal (i.p.) injection at 100 mg/kg. ST-246-treated mice mounted a protective immune response to vaccinia virus infection [1]. ST-246 administered once daily by oral gavage to mice infected intranasally with CV beginning 4 h or delayed until 72 h postinoculation was highly effective when given for a 14-day duration using 100, 30, or 10 mg/kg of body weight. When 100 mg/kg of ST-246 was administered to VV-infected mice, a duration of 5 days was sufficient to significantly reduce mortality even when treatment was delayed 24 h postinoculation. Viral replication in liver, spleen, and kidney, but not lung, of CV- or VV-infected mice was reduced by ST-246 compared to levels for vehicle-treated mice [2]. 物理化学性质： CAS号：869572-92-9 常用中文名：Tecovirimat 常用英文名：Tecovirimat 分子式：C19H15F3N2O3 分子量：376.32900 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C，密闭，干燥 |
盼得（上海）国际贸易有限公司
认证状态：已认证供应商
商品数：4897件
电话：021-60665632
地址：上海市徐汇区中山西路1800号20楼H室
地区： 上海市 上海市 徐汇区
联系人：叶经理
联系人电话：18019361053
邮件：1710932455@qq.com
网址：http://www.iepanda.com/
主要市场：国内、欧美、东南亚、韩国、日本等
年贸易额：
外贸占销售比例：
主要合作伙伴：
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Tecovirimat（mixture of isomers）
- 价格： ￥926.9/5mg ￥775.9/1ml ￥10299.9/100mg ￥3398.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
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- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：替韦立马
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
1710932455
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：ST246
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
351666998
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13311869306
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参考价格：￥3850/10 mM * 1 mL in DMSO