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牛蒡苷

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常用名 牛蒡子苷 CAS号 20362-31-6
价格 ¥需询单/25kg 纯度 70.0%
备货期 需询单 库存 3
 产品详情(用途,包装等)
用途:
Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. IC50 Value:Target: Othersin vitro: Treatment of PC-3 cells with arctiin decreased the cell number in a concentration- and time-dependent manner in serum-containing condition. Arctiin preferentially induced cell detachment, but did not have anti-proliferation or cytotoxic effects in PC-3 cells. The arctiin-induced effect was inhibited by cycloheximide, indicating that protein synthesis was required [1]. Although arctiin, the active component of AL that has been described in the literature, was not able to reduce degranulation in RBL-2H3 cells, a single high-performance liquid chromatography (HPLC) fraction from the AL extract inhibited beta-hexosaminidase release (IC(50) = 22.2 microg/ml) [2]. The growth inhibition caused by arctiin is associated with the down-regulation of cyclin D1 protein expression. Furthermore, thearctiin-induced suppression of cyclin D1 protein expression occurs in various types of human tumor cells, including osteosarcoma, lung, colorectal, cervical and breast cancer, melanoma, transformed renal cells and prostate cancer. Depletion of the cyclin D1 protein using small interfering RNA-rendered human breast cancer MCF-7 cells insensitive to the growth inhibitory effects of arctiin, implicates cyclin D1 as an important target of arctiin [6]. in vivo: Histopathological evaluation of prostate revealed that all the rats in any group developed adenocarcinoma in dorsolateral lobe of prostate, except two rats in 0.1% arctiin treated and one rat in 0.002% arctiin treated groups without prostate adenocarcinoma development [3]. After oral administration of arctiin (30, 60, 120 mg/kgd) for three weeks, the levels of serum creatinine (Scr) and blood urea nitrogen (BUN) and 24-h urine protein content markedly decreased, while endogenous creatinine clearance rate (ECcr) significantly increased [4]. STZ-induced diabetic rats were treated witharctiin at the dosage of 60 or 40 mg/kg/day via intraperitoneal injection for 8 weeks. Blood glucose and 24-h urinary albumin content were measured, and kidney histopathological changes were monitored [5].
物理化学性质:
CAS号:20362-31-6
常用中文名:牛蒡子苷
常用英文名:Arctiin
分子式:C27H34O11
分子量:534.552
密度:1.4±0.1 g/cm3
沸点:756.4±60.0 °C at 760 mmHg
熔点:109 °C
闪点:250.1±26.4 °C
储存条件:?20°C

供应商信息

中山星瑞化工有限公司 认证供应商

认证状态:已认证供应商
商品数:5309件
电话:13380886747
地址:中山市火炬开发区生物谷大道12号综合楼B2-548卡
地区: 广东省 中山市 中山火炬高技术产业开发区
联系人:王经理
联系人电话:13380886747
邮件:3096638339@qq.com
网址:http://
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中山星瑞化工有限公司(Zhongshan Xingrui Chemical Co. , Ltd.)位于广东省中山市,是一家专注于化工原料生产与销售的企业。
公司产品丰富多样,涵盖有机硅新材料、抗氧剂、光稳定剂、化工中间体、食品添加剂、精细化工、 医药中间体、农药原料等多个领域,能满足不同客户的多样化需求。
我们秉持“诚信、质量、服务为本”的经营理念,高度重视产品质量的长期稳定性,确保供货能力可靠,让客户放心。售后服务方面,我们全力投入,无论是技术咨询还是运输问题,客服团队都会耐心解答,为客户提供专业的技术支持和解决方案,以优质服务维护企业信誉,彰显对客户的尊重。
一直以来,中山星瑞化工坚持以质取胜、以诚交友,持续推进技术创新与管理优化,不断提升核心竞争力,致力于与客户构建稳固的信任关系,为客户提供更优质的服务。
展望未来,我们将继续坚守诚信、质量、服务的理念,提升产品质量,创新服务模式,携手各界客户,共同迈向新的辉煌。无论您身处何种行业,只要有化工原料需求,中山星瑞化工都是您值得信赖的优质合作伙伴,期待与您共创美好未来。
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参考价格:¥273/10mg
其他供应商价格:
2024-09-29 牛蒡子苷
价格:¥需询单
2022-02-19 牛蒡子苷
价格:¥247.9
2025-09-17 牛蒡苷
价格:¥需询单
2025-12-29 牛蒡子苷
价格:¥需询单
2024-07-15 牛蒡子苷
价格:需询单
2019-03-05 牛蒡子苷/牛蒡苷
价格:¥118.0
2024-09-13 牛蒡苷,牛蒡子苷
价格:¥需询单
2018-03-25 牛蒡子苷
价格:¥需询单
2016-04-30 牛蒡子苷
价格:¥120.0

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