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毛蕊花糖

毛蕊花糖用途

马鞭草糖是一种半乳糖寡糖(GOS),具有强大的免疫刺激活性。马鞭草糖是一种潜在的天然免疫调节剂[1]。

毛蕊花糖名称

[ CAS 号 ]:
546-62-3

[ 中文名 ]:
毛蕊花糖

[ 英文名 ]:
Verbascose

[英文别名 ]:

MELITOSE
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MELITOSE PENTAHYDRATE
RAFFINOSE PENTAHYDRATE
RAFFINOSE,5-HYDRATE
GOSSYPOSE PENTAHYDRATE

毛蕊花糖生物活性

[ 描述 ]:

马鞭草糖是一种半乳糖寡糖(GOS),具有强大的免疫刺激活性。马鞭草糖是一种潜在的天然免疫调节剂[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[体外研究]

马鞭草糖(25,50,100,200,400μg/mL；12、24、36、48小时)显著提高RAW264.7细胞的生存能力[1]。马鞭草糖具有显著的促进腹腔巨噬细胞吞噬中性红的活性,且呈剂量依赖性,在浓度为200μg/mL时表现出最大的细胞吞噬活性[1]。马鞭草糖诱导NO产生显著增加。马鞭草糖能增强腹腔巨噬细胞吞噬中性红的能力,促进一氧化氮和免疫反应分子如白细胞介素(IL)-6、IL-1β、干扰素(IFN)-α和IFN-γ的释放[1]。

[体内研究]

马巴斯基糖(30、90、120毫克/千克/天；sc；在免疫抑制雌性昆明小鼠的迟发性超敏反应(DTH)中,中等剂量90 mg/kg体重可显著增加脾脏指数、脾脏和血清溶菌酶活性、血清溶血素水平和耳垂肿胀率[1]。

[参考文献]

[1]. Zhuqing Dai, et al. Immunomodulatory activity in vitro and in vivo of verbascose from mung beans (Phaseolus aureus). J Agric Food Chem. 2014 Nov 5;62(44):10727-35.

毛蕊花糖物理化学性质

[ 密度 ]:
1.86g/cm3

[ 沸点 ]:
1185ºC at 760mmHg

[ 熔点 ]:
219-220°; mp 253°

[ 分子式 ]:
C₃₀H₅₂O₂₆

[ 分子量 ]:
828.71800

[ 闪点 ]:
670.5ºC

[ 精确质量 ]:
828.27500

[ PSA ]:
426.98000

[ 折射率 ]:
1.699

[ 储存条件 ]:
2-8°C

毛蕊花糖安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

毛蕊花糖文献

Nutritional potential of rice bean (Vigna umbellata): an underutilized legume.

J. Food Sci. 78(1) , C8-16, (2013)

Rice bean, a less known and underutilized legume, has emerged as a potential legume because of its nutritional potential. The nutritional quality of rice bean is higher as compared to many other legum...

Levansucrase and sucrose phoshorylase contribute to raffinose, stachyose, and verbascose metabolism by lactobacilli

Food Microbiol. 31(2) , 278-84, (2012)

Raffinose family oligosaccharides (RFOs) in food are considered anti-nutritional factors. This study elucidated the role of α-galactosidase (α-Gal), levansucrase, and sucrose phosphorylase for convers...

Quantitation of α-galactosides in Rehmannia glutinosa by hydrophilic interaction chromatography-evaporative light scattering detector.

Phytochem. Anal. 23(6) , 607-12, (2012)

The use of raffinose family oligosaccharides (RFOs) to control several diseases and stimulate immune systems has been studied. Rehmannia glutinosa is reported to contain RFOs; however, there are no re...

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