毒理学数据:
急性毒性：小鼠口经LD50:335 mg/kg
生态学数据:
对水体是极其危害的，即使小量产品不能接触地下水，水道或污水系统，未经政府许可勿将材料排入周围环境。
CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
EV5790000
-
CHEMICAL NAME :
-
Caesium arsenate
-
CAS REGISTRY NUMBER :
-
16331-85-4
-
LAST UPDATED :
-
199610
-
DATA ITEMS CITED :
-
7
-
MOLECULAR FORMULA :
-
As-H3-O4.Cs
-
MOLECULAR WEIGHT :
-
274.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
335 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - wakefulness Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity
-
REFERENCE :
-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 21(1),29,1977
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
116 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - wakefulness Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity
-
REFERENCE :
-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 21(1),29,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
13400 ug/m3/4H/4W-I
-
TOXIC EFFECTS :
-
Brain and Coverings - recordings from specific areas of CNS Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in calcium
-
REFERENCE :
-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 21(1),29,1977
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
4960 ug/m3/4H/17W-I
-
TOXIC EFFECTS :
-
Vascular - BP lowering not characterized in autonomic section Liver - liver function tests impaired Nutritional and Gross Metabolic - weight loss or decreased weight gain
-
REFERENCE :
-
VAMNAQ Vestnik Akademii Meditsinskikh Nauk SSSR. Journal of the Academy of Medical Sciences of the USSR. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1946- Volume(issue)/page/year: (8),10,1978 ** REPRODUCTIVE DATA **
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
DOSE :
-
4600 ug/m3/24H
-
SEX/DURATION :
-
female 1-22 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
-
REFERENCE :
-
VAMNAQ Vestnik Akademii Meditsinskikh Nauk SSSR. Journal of the Academy of Medical Sciences of the USSR. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1946- Volume(issue)/page/year: (8),10,1978
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
DOSE :
-
430 ug/m3/24H
-
SEX/DURATION :
-
female 1-22 day(s) after conception
-
REFERENCE :
-
VAMNAQ Vestnik Akademii Meditsinskikh Nauk SSSR. Journal of the Academy of Medical Sciences of the USSR. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1946- Volume(issue)/page/year: (8),10,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ARSENIC, INORGANIC-air:CA CL 0.002 mg(As)/m3/15M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
|
